Morphotype
|
Activated chromatin Euchromatin
|
Non-activated chromatin Facultative and obligate heterochromatin, euchromatin
|
Structural organization
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Less condensed, unfolding of functional domains (2040 kbp) exhibit
|
Highly condensed
|
DNA methylation (CG sites)
|
DNase I sensitive sites m -sites unmethylated
|
m-sites methylated
|
Nucleosomes
|
DNase I sensitive
|
DNase I resistant
|
Histones
|
H1-deprivated; core histones highly acetylated
|
H1-enriched; association with special H1 isofores, e.g., H5; H2A/H2B under-acetylated; eventually H2A modified by ubiquitin
|
HMG 14/17
|
Present
|
Absent
|
HMG 1/2
|
Present
|
Absent
|
Transcription RNAP/RNP
|
Presence of RNAP and RNP depends on the actual transcription state
|
No
|
