2003 Proteins Proposal Topics

Telomerase recruitment in baker's yeast
Investigating the regulation of period genes involved in circadian rythm
ABC transporters - Multidrug resistance proteins and folate/antifolate transport
ABC transporters - Inhibition of multidrug resistance by stilbene derivitives
The roles of linker histones H1 and H5 in hSWI/SNF nucleosome remodeling
Histone acetyltransferase - testing HBO1 for HAT activity
TLS-CHOP gene translocation-induced mechanism for DOL54 protein induction
Metabolism of tobacco smoke toxicants by Cytochrome P450 isoenzymes
RNA editing by adenosine deaminases - function of ADAR3
Apoptosis - inhibition of caspase function to reduce inflammation due to injury
Inhibition of FXR activation in maintaining cholesterol levels
Assessing osteopontin as a marker for breast cancer onset
Mechanism of Zinc-induced neuronal death
Targeting and regulation of histone methyl transferaseSET7/9

2004 Proteins Proposal Topics

Gene therapy for diabetes - transgenic hepatic insulin expression
Characterization of vitamin D-receptor interactions
Function and level of cardiac cystic fibrosis transmembrante conductance regulator (CFTR) splice variants
Function of P-glycoprotein transporter - inhibition and mutational studies
Complex assembly involving the proteins factors required for nonsense-mediate mRNA decay
The role of dynamin in clathrin-independent endocytosis
The role of CD44 intracellular domain in transcriptional activiation
Transcriptional activity of the NUP98-HOXA9 fusion protein
Characterization of the WRN/FEN-1 interaction
Antibody-mediated plaque clearance in Alzheimer's Disease

2005 Proteins Proposal Topics (already claimed)

Nuclear export of ribosomal proteins
Oxidation modification of ocular proteins
Some aspect of circadian rythm biochemistry
The role of human host cell cyclophilin A in HIV-1 replication