New Links
Slides from Class Presentation
(December 12, 2001) on anticancer compounds, cone snail toxins, alkaloids, etc.
DNA-Cleaving Anticancer
Drugs derived from Microbial Products
Bioactive
Agents from Nature - from plants and microoganisms
Pharmacology Central
- a very thorough site for structures and mechanisms of action of a huge array
of drugs
Marine Siderophores (iron acquisition molecules
used by marine bacteria and algae)
introduction
short summary
of current research
Alison Butler's
siderophore research group - short description
"Aquisition
and Utilization of Transition Metal Ions by Marine Organisms,"
- a review article by Alison Butler, published in Science, July 10, 1998, p.
208.
Haiku
Periodic Table
Monoenoic
and Other Unsaturated Fatty Acids
(Monoenoic acids are long-chain carboxylic acids that
contain a single double bond.)
If you aren't aware of which of these acids is used as a traditional
treatment for leprosy, you can find out at this site. Many other
structurally interesting acids are also discussed.
Organic
Chemistry Help (basic organic chemistry concepts
& list of organic web sites)
Cipro and other Fluoroquinolone Antibiotics
structure
of Cipro
mechanism
of action - DNA gyrase and DNA telomerase inhibitors
DNA
topoisomerases and their inhibition
DNA topoisomerases
- short tutorial
DNA
synthesis - detailed outline of steps
DNA synthesis
- animation of the construction
of the backbone (from the previous links)
Antimicrobial
Chemotherapy - history, structures, categories
(e.g. gyrase inhibitors, cell wall synthesis inhibitors, etc.),
and details on mechanisms of action.