CHE 255                                                             Tentative Biochemistry Class Schedule                                                 Fall 2005

9/7 Introduction, themes of biochemistry                                                                              Ch. 1 (pp. 1-31)
9/9 Cells, Biomolecules                                                                                                               Ch. 1 (pp. 1-31)

9/12 Biomolecules, Properties of water                                                                                     Ch. 1 (pp. 1-31), 2
9/13 Prelaboratory Expt. 1
9/14 Properties of water                                                                                                               Ch. 2 (all)
9/16 Protein Structure - amino acids                                                                                       Ch. 3 (pp. 75-97)

9/19 Protein Structure - peptides                                                                                              Ch. 3 (pp. 75-97)
9/20 Prelaboratory Expt. 2, Intro to methods                                                                        Ch. 3 (pp. 75-97)
9/21 Protein Structure - methods                                                                                             Ch. 3 (pp. 75-97)
9/23 Protein Structure - 3-D structure                                                                                     Ch. 4 (pp. 116-44)

9/26 Protein Structure - 3-D structure                                                                                     Ch. 4 (pp. 116-44)
9/27 Prelaboratory on buffers
9/28 Protein Structure - folding                                                                                                Ch. 4 (pp. 147-153)
9/30 Protein Structure - folding                                                                                               Ch. 4 (pp. 147-153)
            Paper summary due (on protein crystallography)

10/3 Midterm Exam 1 - Ch. 1-4
10/4 Prelaboratory Expt. 3
10/5 Protein Function - oxygen transport                                                                             Ch. 5 (pp. 157-174, box 1)
10/7 Protein Function - oxygen transport                                                                             Ch. 5 (pp. 157-174, box 1)
            ProteinExplorer exercise due

10/10 Protein Function - oxygen transport                                                                             Ch. 5 (pp. 157-174, box 1)
10/11 Prelaboratory Expt. 3 cont., oxygen transport
10/12 Protein Function - oxygen transport                                                                             Ch. 5 (pp. 157-174, box 1)
10/14 Protein Function - introduction to enzymes                                                              Ch. 6 (pp. 190-207)
            ProteinExplorer exercise due

10/17 Protein Function - enzyme kinetics                                                                           Ch. 6 (pp. 190-207)
10/18 Prelaboratory Expt. 3 cont., enzyme kinetics
10/19 Protein Function - enzyme kinetics                                                                           Ch. 6 (pp. 190-207)
10/21 Midterm Exam 2 - Ch. 5-6

10/24-25          Reading Break

10/26 Protein Function - enzyme kinetics                                                                           Ch. 6 (pp. 209-213, box 1 & 2)
10/28 Mid-term grades, course assessment, and exam II

10/31 Zin Obelisk Group Work Task
11/1 Prelaboratory Expt. 4, peer evaluation
11/2 Nucleotides - chemical composition & the genetic material                                 Ch. 8 (pp. 273-279, 282-283)
11/4 Nucleic Acids - the genetic material & replication                                                   Ch. 8 (pp. 280-283, 296-299)

11/7 Nucleic Acids - structure and hybridization                                                             Ch. 8 (pp. 283-293), Ch. 9 (DNA microarrays; pp. 326-327, 328 figures)
11/8 Prelaboratory on Experimental Design
11/9 Lipids                                                                                                                                 Ch. 10 (pp. 343-348)
11/11 Lipids                                                                                                                               Ch. 10 (pp. 348-365)

11/14 Membranes                                                                                                                     Ch. 11 (pp. 369-385)
11/15 Membranes                                                                                                                     Ch. 11 (pp. 369-385)
11/16 Carbohydrates                                                                                                                 Ch. 7 (all pages, but especially pp. 238-252)
11/18 Exam question exercise

11/21 Midterm Exam 3 - Ch. 6 (enz. inhib.), 8, 10-11
11/22 Bioenergetics                                                                                                                   Ch. 13 (pp. 496-516 (pp. 489-495 is bkgd))
11/23 Bioenergetics                                                                                                                   Ch. 13 (pp. 496-516 (pp. 489-495 is bkgd))
11/25-11/28         Thanksgiving Break

11/28 Glycolysis                                                                                                                         Ch. 14 (pp. 521-543)
11/29 Glycolysis                                                                                                                         Ch. 14 (pp. 521-543)
11/30 Glycolysis                                                                                                                         Ch. 14 (pp. 521-543)
12/2 Glycolysis                                                                                                                         Ch. 15 (pp. 560-561, 571-579, Fig. 15-19 on pp. 580)

12/5 Citric Acid Cycle                                                                                                             Ch. 16 (pp. 601-620)
12/6 Citric Acid Cycle                                                                                                             Ch. 16 (pp. 601-620)
12/7Citric Acid Cycle                                                                                                             Ch. 16 (pp. 621-623)
12/9 Midterm Exam 4 - Ch. 7, 13, 14, 15 & 16

12/12 Oxidative Phosphorylation                                                                                         Ch. 19 (pp. 690-704)
            Paper summary due
12/13 Oxidative Phosphorylation                                                                                         Ch. 19 (pp. 704-716)
12/14 Oxidative Phosphorylation                                                                                         Ch. 19 (pp. 716, 718)

12/20 Comprehensive Final Exam 8:00-10:00 a.m.