Telomerase recruitment in baker's yeast
Investigating the regulation of period genes involved
in circadian rythm
ABC transporters - Multidrug resistance proteins and
folate/antifolate transport
ABC transporters - Inhibition of multidrug resistance
by stilbene derivitives
The roles of linker histones H1 and H5 in hSWI/SNF nucleosome
remodeling
Histone acetyltransferase - testing HBO1 for HAT activity
TLS-CHOP gene translocation-induced mechanism for DOL54
protein induction
Metabolism of tobacco smoke toxicants by Cytochrome P450
isoenzymes
RNA editing by adenosine deaminases - function of ADAR3
Apoptosis - inhibition of caspase function to reduce
inflammation due to injury
Inhibition of FXR activation in maintaining cholesterol
levels
Assessing osteopontin as a marker for breast cancer onset
Mechanism of Zinc-induced neuronal death
Targeting and regulation of histone methyl transferaseSET7/9
2004 Proteins Proposal Topics
Gene therapy for diabetes - transgenic hepatic insulin
expression
Characterization of vitamin D-receptor interactions
Function and level of cardiac cystic fibrosis transmembrante
conductance regulator (CFTR) splice variants
Function of P-glycoprotein transporter - inhibition and
mutational studies
Complex assembly involving the proteins factors required
for nonsense-mediate mRNA decay
The role of dynamin in clathrin-independent endocytosis
The role of CD44 intracellular domain in transcriptional
activiation
Transcriptional activity of the NUP98-HOXA9 fusion protein
Characterization of the WRN/FEN-1 interaction
Antibody-mediated plaque clearance in Alzheimer's Disease
2005 Proteins Proposal Topics (already claimed)
Nuclear export of ribosomal proteins
Oxidation modification of ocular proteins
Some aspect of circadian rythm biochemistry
The role of human host cell cyclophilin A in HIV-1 replication